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Kexing launched the world's first phase III clinical study of bivalent inactivated enterovirus vaccine. On December 13th, the first volunteer was enrolled in the phase III clinical study of bivalent inactivated enterovirus vaccine developed by Beijing Kexing Biological Products Co., Ltd., a subsidiary of Kexing Holding Biotechnology Co., Ltd. (hereinafter referred to as "Kexing"). The vaccine is used to prevent hand, foot and mouth disease caused by enterovirus 71 (EV71) and coxsackie virus 16 (CA16). A multicenter, randomized, double-blind, controlled study design was adopted in this phase III clinical study to evaluate the protective efficacy, safety and immunogenicity of the vaccine in children aged 6-71 months.Market News: Austria provides 1,000 euros to Syrian refugees to help them return home.Ningbo Shipping Exchange: The freight rate of the United States and the West increased sharply, and the comprehensive index stopped falling and rose. This week, the Ningbo Export Container Freight Index (NCFI) of the Maritime Silk Road Index released by Ningbo Shipping Exchange closed at 1722.8 points, up 4.8% from last week. Among the 21 routes, the freight index of 7 routes rose and that of 14 routes fell. Among the major ports along the "Maritime Silk Road", the freight index of 4 ports rose and that of 12 ports fell. The overall shipment of the market has increased, liner companies have reduced their route capacity, and at the same time, they have adjusted the port-calling order of some routes in the west of the United States, and the freight rate has increased more than that in the east of the United States. The freight index of the US-East route was 1808.1 points, up 10.0% from last week. The freight index of the US-West route was 2092.1 points, up 43.5% from last week.

Analysis: the potential weakness of Canada's manufacturing industry still exists. Forexlive: Canada's manufacturing industry rebounded strongly, mainly driven by petroleum products and automobiles. However, the year-on-year data decline shows that some potential weakness still exists.BMO raised the target price of Chevron from $170 to $175.Shanghai Shipping Exchange: The transportation demand of Persian Gulf routes remained high, and the market freight rate continued to rise this week. On December 13th, according to the news of Shanghai Shipping Exchange, this week, the export container transportation market in China was basically stable, and different routes were divided due to their different trends of supply and demand fundamentals, and the comprehensive index rose. On European routes, the growth of transportation demand is weak, the fundamentals of supply and demand lack further support, and the booking price in the spot market drops slightly. On the North American route, the transportation demand is generally stable, and the relationship between supply and demand is basically balanced. Major airlines push the freight rate up, and the spot market booking price rises sharply. On the Persian Gulf route, the transportation demand remained high, and the market freight rate continued to be supported by the local tension. This week, the market freight rate continued to rise. On the Australia-New Zealand route, the local demand for various materials showed signs of stabilization, the fundamentals of supply and demand improved, and the market freight rate stopped falling and rebounded. On the South American route, the transportation demand lacks the motivation for further growth, and the fundamentals of supply and demand weaken. This week, the spot market booking price dropped slightly.

State-owned Assets Supervision and Administration Commission (SASAC): Actively expand effective investment, improve investment efficiency, and focus on the layout of a number of major projects with strong traction and long-term benefits. The Party Committee of the State Council SASAC held a special meeting. The meeting stressed that it is necessary to promote central enterprises to improve their ability to cope with cyclical fluctuations, continue to exert efforts in performance appraisal, quality improvement and efficiency improvement, and economic operation, and strive to simultaneously improve efficiency and efficiency indicators, and strive to achieve development with stronger scientific and technological attributes and greater driving role; Actively expand effective investment, improve investment efficiency, focus on "two" and "two new" layout of a number of major projects with strong traction and long-term benefits; We will do a better job in helping small and medium-sized enterprises, promote central enterprises to deepen strategic cooperation in the industrial chain, take the lead in paying off debts owed by private enterprises, and go all out to stabilize employment, supply and flow, so as to better help the national economy continue to pick up. It is necessary to promote the central enterprises to improve the supply capacity of common technologies, further highlight the key points and strengthen the key core technologies, especially in areas with large investment and long cycle; Further highlight the original innovation, explore and create a "policy enclave", strengthen the applied basic research, and deeply root the "root technology"; Further highlight the transformation of achievements, promote the construction of a number of major pilot projects by central enterprises, and constantly open up the "last mile" of the transformation of scientific and technological achievements into real productive forces, so as to better help high-level science and technology stand on its own feet. (SASAC)COMEX silver fell 2.00% in the day and is now quoted at $30.99 per ounce. COMEX silver fell to $31 per ounce, down 1.97% in the day.Sixteen people have been sentenced for the anti-corruption storm in football. Since Li Tie, the former head coach of China Men's Football Team, was investigated in November 2022, a new round of anti-corruption storm has blown up in China football. The storm has become more and more fierce, involving not only players gambling and bribery at the top of the club, but also corrupt elements at the top of the Football Association and even the General Administration of Sports. Today, Li Tie's case and Du Zhaocai's case, the former vice chairman of the Chinese Football Association, were pronounced in the first instance. Up to now, 16 people have been sentenced in China football (Beijing Daily)